With the rapid development of precision medicine, targeted drugs have become a key approach in cancer treatment. Unlike traditional chemotherapy, targeted therapy “hits” specific molecules or signaling pathways in tumor cells, minimizing damage to normal tissues.
1. EGFR-targeted drugs
Used for patients with EGFR mutations in lung cancer. These drugs block signaling pathways to inhibit tumor growth. Different generations vary in resistance patterns and control of brain metastases.
2. ALK/ROS1-targeted drugs
Designed for driver gene rearrangements, especially in non-smoking lung cancer patients. They effectively control lung and brain lesions with manageable side effects.
3. VEGF/VEGFR-targeted drugs
Block tumor angiogenesis, commonly used for liver, kidney, and colorectal cancers. Blood pressure and bleeding risks should be monitored.
4. HER2-targeted drugs
Used for HER2-overexpressing breast cancer. They block signaling or engage immune mechanisms to inhibit tumor growth and reduce recurrence risk.
5. PARP inhibitors
Used for BRCA-mutated cancers, causing tumor cell death due to impaired DNA repair. They are an important addition to precision therapy.
6. KRAS-targeted drugs
Breakthroughs for previously “undruggable” KRAS mutations. Some G12C inhibitors have entered clinical practice, offering new options for patients lacking effective therapies.
7. Multi-target TKIs
Act on multiple targets, suitable for liver, kidney, and thyroid cancers. Treatment can be adjusted according to patient tolerance.
Conclusion
Targeted drugs provide precision therapy through different mechanisms. Choice depends on genetic testing and professional evaluation. With new targets under research, targeted therapy will reach more patients and offer more systematic and controllable treatment solutions.
Eltromin 25/50 Eltrombopag
Enatinib 4/10 Lenvatinib
Lynparib Olaparib
Coltinib Upadacitinib
Alvonib Osimertinib
Techno
Well-known pharmaceutical company in Bangladesh：https://www.radiantpharmacil.com
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